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Morphology of Mycobacterium Tuberculosis MTB is a slow growing facultative intracellular parasite was first discovered in 1882 by Robert Koch

January 31, 2019 0 Comment

Morphology of Mycobacterium Tuberculosis
MTB is a slow growing facultative intracellular parasite was first discovered in 1882 by Robert Koch. They require oxygen to grow and it does not retain any common bacteriological stain (gram stain) due to high lipid contents. That’s why it is neither gram negative neither gram positive. The growth of MTB occurs on selective medium called Lowenstein – Jensen medium, incubated at 37°C for upwards of eight weeks for growth and reason for the slow growth rate to many known antibiotics which are distinctive features of the tuberculosis bacillus is low permeability of its cell wall (Moravkova et al., 2011). Tuberculosis bacillus is an aerobic non sporing curved or smooth bacillus of 0.2? 0.6 × 1-10 ?m in dimensions. Thickness of the cell wall is much greater than the other bacteria and contain high amount of lipid and during the presence of extra lipid, drug resistance occurs due to low permeability of the drug (Öztürk et al., 2013).